Two sample MR report
HLA-A_T Proliferating against bbj-a-88
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 8 | 0.0883386 | 0.6283936 | 0.8928037 |
| Weighted median | 8 | -0.0326190 | 0.0297981 | 0.2736614 |
| Inverse variance weighted | 8 | -0.0809970 | 0.0298045 | 0.0065754 |
| Simple mode | 8 | -0.0116819 | 0.0500497 | 0.8221243 |
| Weighted mode | 8 | -0.0217737 | 0.0451149 | 0.6440865 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 19.85738 | 6 | 0.0029360 |
| Inverse variance weighted | 20.09833 | 7 | 0.0053612 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0650091 | 0.2409315 | 0.7963359 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0001831 | 1e-07 | TRUE | 0.2069208 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
